Our new Very clear+ tissue clearing procedure is the sole strategy that delipidates samples without alter in morphology and with nominal effect on structural integrity.
Megatome is really a vibrating microtome intended to part a wide array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform surface area profile, along with small tissue problems and knowledge loss.
Antibodies may take weeks to diffuse by means of just a few millimeters of tissue, by using a steep labeling gradient from surface to Main.
Megatome is created for precision: the blade vibrates at an increased frequency and bigger amplitude vary than other microtomes, and encompasses a special deflection Handle mechanism.
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Megatome is a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to megatomi.com intact human Mind hemispheres – with minimum tissue destruction and data loss.
It’s the perfect time to improve your microtome to Megatome. With exact substantial-frequency slicing for an unmatched range of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous purposes.
The SmartSPIM mild sheet microscope gives unparalleled resolution and acquisition velocity through intact tissue volumes, while its modular style and design means that you can improve and customise person factors.
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Leverage the Obvious+ tissue clearing method, as well as eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Vital highlights and attributes incorporate:
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